In scientific research with systematic review method that compares the effectiveness of cannabis as an antiemetic drug obtained from cannabis is effective as an antiemetic drug compared to prochlorperazine, metoclopramide, chlorpromazine, thiethylperazine, haloperidol, domperidone, or alizapride, but its use is very limited in dosage, because some patients experience symptoms psychotropic from cannabis which is very dangerous such as dizziness, depression, hallucinations, paranoia, and also arterial hypotension.
Greece as one of the locations of the origin of the spread of the progress of human civilization gave birth to a collection of medical knowledge. The book “Materia Medica” written by Dioscorides (1 S.M.) in the days after the Romans ruled Greece became a reference book for scientists from many nations for 1500 years. In the “Materia Medica”, Dioscorides notes cannabis as a plant whose stem fiber is good and strong for rope making, while seeds are useful for treating ear pain and loss of sexual desire (Dioscorides 1968 – 3,165 – p. 3,90). In “de facultative alimentorum”, Claudius Galen or better known as Galen (128-201 AD) notes that Greek people at that time ate a cake with cannabis ingredients called cum aliis tragematis & quot for joy at a banquet.
While as a drug, Galen noted that cannabis is used to relieve pain and remove gas from the digestive tract. Other Greek thinkers named Gaius Plinyus Secundus or “Pliny the Old” (23-79 AD) recorded the use of cannabis in “Naturalis Historia” as juice to remove worms and small animals that enter the ear, eliminate stomach aches, heal stiff joints, rheumatism and skin diseases.
This collection of medical knowledge from the Greeks then continued its development by the Arabs. The Arabs were the nation that had the most amount of medical knowledge about cannabis compared to other nations before the 20th century. The first record of medical benefits of cannabis in Arabic literature arose from the writings of a doctor named Ibn-Masawayh (857 AD) who mentioned its use as a medicine for ear pain. In the 10th century, the father of Arabic medicine, Ibn Sinna or more famous in the world with Avicenna also noted the benefits of cannabis to remove gas from the stomach.
Epilepsy is a disease recorded by the Arabs as a disease that can be cured with cannabis. Ibn al-Badri in the 15th century said that cannabis can cure epileptic seizures in an instant (Lozano, 1989).